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PASSIONFLOWER

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Medicinal Uses

anxiety

constipation

indigestion

insomnia

nervousness

mild infections

hysteria

neurasthenia

neuralgia

neurosis

insomnia

epilepsy

painful menstruation (dysmenorrhea)

boils

cuts

earaches

inflammation

intractable insomnia

nerve pain

seizures

asthma associated with spasms and tension

attention deficit hyperactivity disorder (ADHD)

morphine addiction

smoking cessation

alcoholism

increased libido

increased testosterone levels

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  • Passiflora incarnata is an excellent ally for general tension. Tension that manifests as sleeplessness, tension that manifests as muscle pain, or tension that manifests as anxious thoughts.

  • Passionflower is commonly utilized to respond to insomnia, aiding transition into a natural sleep without any “narcotic” hangover. Passionflower works directly on the central nervous system to help lull us to sleep. It is important to note that Passionflower will not force sleep, but rather supports normal sleep that may have been disrupted by stress, muscle spasms, etc.

  • It may also be used wherever an antispasmodic is necessary, such as in seizures or Parkinson’s disease. It is also effective for nerve pain and viral infections of the nerves known as shingles. Furthermore, it’s been chronicled to be of use for delirium tremens, whooping cough, drug withdrawal, teething, hysteria, mania, and even flatulence. Evidence suggests that Passionflower may have a benzodiazepine-like calming action.

  • Passionflower has the most defined sedative effect of all the nervines. It is extremely effective in cases of circular thinking that cause insomnia. “I have had patients tell me it’s like they have a talk radio station on in their heads and they can’t find the off switch,” said David Winston. “Passionflower is the off switch”. 

  • Passionflower is known to be a depressant to the motor side of the spinal cord (hence its use for muscle spasms), slightly reducing arterial pressure while increasing the rate of respiration. It is also helpful where functional heart palpitations are present and stress is due to concerns of the heart, as opposed to hops which are similar in action but better suited to intellectual worry, or cares of the mind.

Constituents​

  • Passiflora contains: Alpha-alanine, apigenin, chrysin, citric acid (tricarboxylic acid), coumarin, cyclopassifloic acids A-D, cyclopassiflosides I-VI, diethyl malonate, edulan I, edulan II, flavanoids, glutamine, gynocardin, harmane (aka aribine), haraline, harmalol, harmine, harmol, homoorientin, isoorientin, isoschaftoside, isovitexin, kaempferol, loturine, lucenin-2, lutenin-2, luteolin, n-nonacosane, orientin, passicol, passiflorine, passifloric acid, pectin, phenolic acids, phenylalanine, proline, prunasin, quercetin, raffinose, sambunigrin, saponarin, saponaretin, saponarine, schaftoside, scopoletin, serotonin, sitisterol, and stigmasterol.

  • Other constituents include phenolic compounds, fatty acids (linoleic, linolenic, palmitic, oleic, and myristic acids), formic and butyric acids, coumarins, phytosterols, and essential oils [8]. About 294 volatile compounds have been identified in several passion fruit extracts [12]. Maltol has also been discovered in various Passiflora species, which has documented sedative effects, as well as the neurotransmitter serotonin

  • Flavonoids and alkaloids, including harmala, though there is no evidence to support that this alkaloid occurs in amounts large enough to be of concern for kidney toxicity. 

  • While flavonoids are generally considered among the most active constituents of Passionflower, there has been little definitiveness for attributing its sedative action to a single chemical compound or group of compounds.

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Energetics/ Organoleptics

  • ORGANOLEPTIC PERSPECTIVE:  the look of the intricate and delicate flower is a visual clue to its indications, being most successful in fragile and delicate conditions, namely pediatric or geriatric use as well as fragile emotional states.

  • ENERGETICS: Slightly cooling and drying, mildly bitter.  As a herb for the nervous system, Passionflower's ability to smooth the flow of energy is recognized as antispasmodic.  It helps reduce or soothe erratic or convulsive nerve impulses throughout the body. In this way, Passionflower can help to calm and cool an overheated or overstimulated nervous system.  Passionflower is indicated for those who “need to have their hearts calmed and grounded so that they can be connected to others”. It suits those that are prone to anxiety, hysteria, and heart symptoms when overstimulated. When “Passionflower types” go into overload they become exhausted physically and mentally in a way that prevents them from connecting to others, focused inward on their own sensations and feelings. This can cause long-term stress, a condition for which Passionflower is perfectly suited. TCM echoes this by indicating Passionflower for Qi imbalance caused by an overload rather than a blockage.

  • SPIRITUAL PROPERTIES:  This plant is a conductor meaning that it attunes the mind to higher frequencies, by sharpening the antenna and preparing the nervous system to receive subtle information. Clairvoyance, heightened spiritual states, greater awareness, channeling and even peak experiences of a religious nature take place much more easily with passion flower.

  • PLANET: ruled by Venus

  • CHAKRA: The crown chakra is stimulated, with the energy likely to move in both directions, vibrating and creating resonance with the 6th and 8th chakras. 

  • MERIDIANS/ ORGANS:  KIDNEYS + NECK: There is a strengthening of the nadis (energetic pathways) in the neck, wrist and arm areas. There is also a strengthening of the kidney meridian, especially where ir runs through the interstitial spaces in the chest.

  • SOUL BODY: The soul body is cleansed and there is more attunement between the etheric, emotional, and mental bodies. For many people, this causes deep reverence, and it is easier to release energy that may accumulate in the etheric body. 

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Contradictions​

  • Passionflower is considered extremely safe and gentle. It’s only known contraindications are, as is the case with many plant medicines, pharmaceuticals. Passionflower may elevate the effects of prescription sedatives, antispasmodics and anxiolytics, so use cautiously (or not at all) together. And do not ever use Passionflower with MAOIs 
  • John Fyfe, MD, states “That passiflora is not toxic is evidenced by the fact that it has been given in 10-15 drop doses every hour for six and eight hours, to infants less than one year old, without the slightest evidence of deleterious effects. It has also been administered to the very sick and weak without harmful action”

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History

  • The first recorded use of Passionflower dates back to the Aztecs, and was eventually widely cultivated in Europe after the Spanish conquistador era. 

  • The name Passionflower is derived from flos passionis, a translation of fior della passione, a name applied to the plant in Italy to note religious symbolism.

  • The floral structure was seen as symbolizing the implements of the crucifixion, a symbolic reflection of the Passion of the Christ. The white and purple in the flower were said to symbolize heavenly purity, five stamens for the five wounds Jesus suffered, and three style for the three nails used to bind him to the cross .

  • The species name incarnata means “made of flesh or flesh-colored” 

  • Nicolas Monardes, a Spanish doctor working in Peru, was the first to document the use of Passionflower in 1569.

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Common Names

Wild passion flower, Old field apricot, Holy-Trinity flower, Molly-pop, Passion vine, Pop-apple, Maracuja, Granadilla, Maycock,

White sarsaparilla, Purple pa, Apricot Vine,  Passiflora, Purple Passionflower, Clock Face Flowers (Japan).

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Botanical Name

Passiflora incarnata

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Family

Passifloraceae

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Parts Used

Native Americans used the root in poultice preparation for boils, cuts, earaches, and inflammation. Typically the aerial parts are the most commonly used medicinally. Though is it not noted to have any medicinal properties, the passionflower fruit is edible and is high in niacin (vitamin B3) and is commonly used to make jams or jellies. The young leaves and buds are commonly eaten as vegetables, and sometimes the flowers are made into syrup.

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Therapeutic Actions

​analgesic

anodyne

anxiolytic

aphrodisiac

anti-asthmatic

anti-bacterial

anti-fungal

anti-convulsant

anti-depressant

anti-diabetic

anti-oxidant

anti-seizure

anti-spasmodic

anti-tussive

cardioprotective

chemoprotective

diuretic​

hypnotic

nervine

neuroprotective

hypotensive

sedative

vermifuge​

Proper Use

Passionflower is most commonly administered as tea, tinctures, and encapsulations. It is also sometimes found in relaxing bath blends and sleeping pillows, and even sedative chewing gums.

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Apart from some individuals being sensitive to it, Passiflora is remarkably safe and can be consumed to up to 6 grams a day without adverse effects. However, most trials use 2-4g per day

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Dosing suggestion varies quite a bit as there is a wide range for cause of need for Passionflower. According to Boericke’s Materia Medica, “large dosage of the mother tincture” (30-60 drops) should be repeated several times per day. However Priest and Priest suggest a maximum dose of 15 drops, and the German monograph suggests six grams of the herb per day in an infusion. It is always the best practice to consult with a licensed healthcare professional to figure out which dosing of this or any herb is best for your specific needs. Lastly, a good note to bear in mind regardless of dosing: Felter & Lloyd’s suggests that Passiflora is slow acting and more effective in the second twenty-four hours rather than the first.  

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Formulary

Passionflower is commonly paired with Valerian and Hawthorn to aid digestive spasms, gastritis, and colitis. It is not necessarily strong enough to be utilized as a singular painkiller, but works well when combined with other anodyne herbs such as Jamaican Dogwood, Cramp Bark, and Valerian. Passionflower also pairs well with Motherwort for menopausal-specific insomnia, and Skullcap for bruxism (grinding one’s teeth during sleep).

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The following is a list of herbs that can be prescribed with Passiflora to boost its therapeutic properties:

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  • Valerian. This herb does help reduce anxiety however its proudest achievement is its ability to induce sleep in patients. In many ways its actions are similar to Passiflora however, in my opinion, Valerian may be a more potent inducer of sleep, where as Passion flower is more effective at reducing anxiety.
     

  • Hops. Best known for their use in the production of beer, hops also reduce anxiety and insomnia. While not as well researched as Valerian and Passion flower, Hops should not be overlooked by the stressed out individual or someone suffering from sleep problems.
     

  • Zizyphus. A Chinese herb, Zizyphus has traditionally been used for the treatment of anxiety and insomnia. However it may also be useful in the reduction of pain.
     

  • Chamomile. Chamomile is a calming herb that has a powerhouse of science backing its actions. Often used as a relaxant, Chamomile also soothes gastric upset and reduces pain and inflammation and because Chamomile has mood elevating effects, it can help with mild depression.

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Cultivation

  • Passiflora incarnata is a fast-growing perennial vine belonging to the wildly diverse Passiflora genus. Passiflora is native to the tropical and semi-tropical regions of the Americas. 

  • Passionflower should be planted in early spring. It is considered fully hardy but frost tender, and fairly easy to grow. It likes partial to full sun and well-drained but reliably moist soils. It is not overly sensitive to particular soil acidity or alkalinity.

  • Due to Passiflora’s relationship with the Heliconius butterfly, and its ever changing and deceptive leaf shape, it can often be very well camouflaged in its environment.  

  • When collecting passion flower for medicine, it is important to consider what is being treated.  For fungal infections it may be best to damage the leaves a few hours or days before harvesting as this has been shown to increase the anti-fungal agents located in the plant.  If the antioxidant effects are the desired effects, species choice will make a difference, P. edulis, P. setacea, P. nitida, P. tenufida, all have high antioxidant levels, with P. malformis leaf aqueous extract shown to have the highest antioxidant profile.

  • The pulpy fruit or “maypop” develops in two to three months after flowering and may be harvested from July to October 

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Research & References

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Akhondzadeh, Shahin & MD, H. & Vazirian, Mohsen & Shayeganpour, Anooshirvan & PharmD, H. & MSc, M.. (2001). Passionflower in the treatment of generalized anxiety: A pilot double-blind randomized controlled trial with oxazepam. Journal of Clinical Pharmacy and Therapeutics. 26. 363 - 367. 10.1046/j.1365-2710.2001.00367.x. 

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Gwang-Ho Kim, et al. (2019).  Improvement in neurogenesis and memory function by administration of Passiflora incarnate L. extract applied to sleep disorder in rodent models. Journal of Chemical Neuroanatomy, 10.1016/j.jchemneu.2019.03.005, (2019).

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Jeewon Lee, Han-Young Jung, Soyoung Irene Lee, Ji Ho Choi and Shin-Gyeom Kim, (2020).  Effects of Passiflora incarnata Linnaeus on polysomnographic sleep parameters in subjects with insomnia disorder.  International Clinical Psychopharmacology, 10.1097/YIC.0000000000000291, 35, 1, (29-35), (2020).

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Natural Standard Research Collaboration.  (2008) . An Evidence-Based Systematic Review of Passion Flower (Passiflora Incarnata L.) . Journal of Dietary Supplements, 5:3, 310-340, DOI: 10.1080/19390210802414360
 

Samantha Bedell, Jacob Wells, Qinfeng Liu and Chris Breivogel.  (2019).  Vitexin as an active ingredient in passion flower with potential as an agent for nicotine cessation: vitexin antagonism of the expression of nicotine locomotor sensitization in rats. Pharmaceutical Biology, 10.1080/13880209.2018.1561725, 57, 1, (8-12), (2019).

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